Abstract:
The objective of preparing this report is to find out whether Indapamide (an antihypertensive
drug) could be launched in the market or not, from view point of new company. Indication: Indapamide is a diuretic used for the treatment of hypertension (high blood
pressure), alone or in combination with other antihypertensive drugs as well as for the
treatment of salt and fluid retention associated with congestive heart failure or edema from
pregnancy.l
High blood pressure adds to the workload of the heart and arteries. If it continues for a long
time, the heart and arteries may not function properly. This can damage the blood vessels of
the brain, heart, and kidneys resulting in a stroke, heart failure, or kidney failure. High blood
pressure may also increase the risk of heart attacks. These problems may be less likely to
occur if blood pressure is controlled.2
lndapamide works by preventing the kidney from reabsorbing (retaining in the body) salt and
water that is destined to be eliminated in the urine. This results in increased urine output
I diuresis). Indapamide also is thought to reduce the salt in the smooth muscle of the walls of
c-lood vessels. (The salt ultimately is eliminated in the urine.) The loss of salt from the muscle
..
Description:
This thesis submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy (B.Pharm) in East West University, Dhaka, Bangladesh.