Abstract:
The purpose of this study was to understand and investigate the cytotoxic and antimicrobial
effect of the traditional medicinal plant Aphanamixis polystachya.
Toxicologically it is classified under the family Meliaceae. In this paper the study was
conveyed on the methanol extract of the fruit of Aphanamixis polystachya. Many
researches were done on this plant species by many scholars at different time period but
the intention of the study was to emphasize on the possibility of its cytotoxic property. To
prove the cytotoxic property and detect its intensity, the Brine Shrimp Lethality Bio-assay
and to measure the anti-microbial property Disk-diffusion method (Kirby-Bauer) was
chosen. After collection, identification and drying the fruit sample, extraction was
performed by using methanol solvent system. The extracted components were used to
measure the cytotoxicity level over Brine Shrimp Nauplii and anti-microbial property was
tested over Candida albicans, Shigella dysentery and Staphylococcus aureus.
Description:
This thesis submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy (B.Pharm) in East West University, Dhaka, Bangladesh.