Abstract:
The objective of this research is to study the phytochemical properties of methanolic
extracts of Polygonum lanatum, a plant of Polygonacea family. The phytochemical
evaluation was carried out by performing several test TLCs, preparative TLC, & IR test.
Polygonum lanatum, a tropical herb, is commonly known as Bishkatali. The plant
belongs to family Polygonacea, possessing analgesic, diuretic and anti-inflammatory
activity. The plant is distributed in Southeast Asia. Isolation of sterols, terpenoids,
flavonoid glycosides, coumaryl glycoside, lignans, quinones, 6-methoxyplumbagin was
resulted through the phytochemical investigation on this plant. The leaves are slightly
bitter, cure inflammation, skin diseases, laxative, bronchitis, nervous affection,
leucoderma, biliousness and good in small pox. The plant possesses nutritional value
including-carotene, saponins, cholesterol, glucoside, enhydrin and so on. It is reported
that plant possesses Antioxidant, Hepatoprotective, CNS Depressant, Analgesic and
Antidiarrheal activity. Thin-layer chromatography (TLC) is a mature and very established
technique, frequently used in many fields of applications ranging from natural product
analysis to chemical or pharmaceutical applications. Fourier Transform Infrared
Spectroscopy (FTIR) identifies chemical bonds in a molecule by producing an infrared
absorption spectrum. The spectra produce a profile of the sample, a distinctive molecular
fingerprint that can be used to screen and scan samples for many different components.
FTIR is an effective analytical instrument for detecting functional groups and
characterizing covalent bonding information. TLC & IR test performed to investigate
bioactive natural compounds from P. lanatam. Some bands were observed through those
tests.
Description:
This thesis submitted in partial fulfillment of the requirements for the degree of Bachelor of Pharmacy (B.Pharm) of East West University, Dhaka, Bangladesh.