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<title>Thesis 2007</title>
<link>http://dspace.ewubd.edu:8080/handle/123456789/4092</link>
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<dc:date>2026-04-05T23:33:26Z</dc:date>
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<title>Identification of Genetic Promoter through Stochastic Approach</title>
<link>http://dspace.ewubd.edu:8080/handle/123456789/4093</link>
<description>Identification of Genetic Promoter through Stochastic Approach
Ghyas, Qazi Adnan
Analysis of a gene sequence, which is transcribed into RNA and then translated&#13;
inti protein, is a difficult task. If this could be achieved, it would make possible&#13;
better understand how the organisms are developed from DNA information.&#13;
The behavior of gene is highly influenced by promoter sequences residing&#13;
up stream or downstream of the Transcription Start Site (TSS). The promoter&#13;
recognition pro,&#13;
access is a part of the complex process where genes interact with&#13;
each other over time and actually regulates the whole working process of a cell.&#13;
This paper attempts to develop an efficient algorithm that can successfully&#13;
distinguish promoters and non promoters by analyzing statistical data. A&#13;
learning model is developed from the known dataset to predict the unknown&#13;
ones. Results: We have developed an efficient algorithm that can successfully&#13;
distinguish genes from non-gene sequences by analyzing statistical data. A&#13;
learning model is initially developed to train the Support Vector Machine&#13;
(SVM) to identify distinctive features between gene and non gene. Then this&#13;
context was used to predict other foreign sequence by the SVM. Our system&#13;
has been tested using standard plant prom data sequence from the EMBL and&#13;
the performances are: 0.86 for the Sensitivity and 0.90 for the specificity.&#13;
Identification
This thesis submitted in partial fulfillment of the requirements for the degree of Masters of Science in Computer Science and Engineering of East West University, Dhaka, Bangladesh
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<dc:date>2007-12-06T00:00:00Z</dc:date>
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